Distinct germline polymorphisms underlie glioma morphologic heterogeneity

Two recent genome-wide association studies reported that single nucleotide polymorphisms (SNPs) in (or near) TERT (5p15), CCDC26 (8q24), CDKN2A/B (9p21), PHLDB1 (11q23), and RTEL1 (20q13) are associated with infiltrating glioma. From these reports it was not clear if the SNP associations predispose...

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Main Authors: Jenkins, Robert B., Wrensch, Margaret R., Johnson, Derek, Fridley, Brooke L., Decker, Paul A., Xiao, Yuanyuan, Kollmeyer, Thomas M., Rynearson, Amanda L., Fink, Stephanie, Rice, Terri, McCoy, Lucie S., Halder, Chandralekha, Kosel, Matthew L., Giannini, Caterina, Tihan, Tarik, O’Neill, Brian P., Lachance, Daniel H., Yang, Ping, Wiemels, Joseph, Wiencke, John K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062955/
https://ncbi.nlm.nih.gov/pubmed/21356187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2010.10.002
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