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Simultaneous Bioanalysis of L-Arginine, L-Citrulline, and Dimethylarginines by LC-MS/MS

PURPOSE: L-Arginine (ARG) is converted to nitric oxide (NO) and L-citrulline (CIT) by endothelial nitric oxide synthase which is competitively inhibited by asymmetric dimethylarginine (ADMA). We have developed a liquid chromatography-mass spectrometric method for the simultaneous determination of en...

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Main Authors: Shin, Soyoung, Fung, Sun-Mi, Mohan, Srinidi, Fung, Ho-Leung
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062941/
https://ncbi.nlm.nih.gov/pubmed/21282076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.01.006
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