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Estimation of nitric oxide synthase activity via LC-MS/MS determination of (15)N(3)-citrulline in biological samples
RATIONALE: We showed that the metabolite peaks of (15)N(3)-citrulline ((15)N(3)-CIT) and (15)N(3)-arginine ((15)N(3)-ARG) could be detected when (15)N(4)-ARG was metabolized by nitric oxide synthase (NOS) in endothelial cells. The usefulness of these metabolites as potential surrogate indices of nit...
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| Publicado no: | Rapid Commun Mass Spectrom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566859/ https://ncbi.nlm.nih.gov/pubmed/26349467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.7124 |
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