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Intracellular L-arginine concentration does not determine NO production in endothelial cells: Implications on the “L-arginine paradox”

We examined the relative contributory roles of extracellular vs. intracellular L-arginine (ARG) toward cellular activation of endothelial nitric oxide synthase (eNOS) in human endothelial cells. EA.hy926 human endothelial cells were incubated with different concentrations of (15)N(4)-ARG, ARG, or L-...

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Autors principals: Shin, Soyoung, Mohan, Srinidi, Fung, Ho-Leung
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210395/
https://ncbi.nlm.nih.gov/pubmed/21986532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.112
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