Caricamento...

Efficient Synthesis of a Novel Resorcyclide as Anticancer Agent Based on Hsp90 Inhibition

The highly efficient synthesis of a novel heat shock protein 90 (Hsp90)-based anticancer agent, triazole-cycloproparadicicol (5), is described. The key step involves a fragment coupling using “click chemistry.” The preliminary biological evaluation of triazole-cycloproparadicicol is also reported....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lei, Xiaoguang, Danishefsky, Samuel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062907/
https://ncbi.nlm.nih.gov/pubmed/21442009
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !