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Structures of β-hairpin Antimicrobial Protegrin Peptides in Lipopolysaccharide Membranes: Mechanism of Gram Selectivity Obtained From Solid-State NMR
The structural basis for the Gram selectivity of two disulfide-bonded β-hairpin antimicrobial peptides (AMPs) is investigated using solid-state NMR spectroscopy. The hexa-arginine PG-1 exhibits potent activities against both Gram-positive and Gram-negative bacteria, while a mutant of PG-1 with only...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062705/ https://ncbi.nlm.nih.gov/pubmed/21302955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101975v |
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