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Roles of Arginine and Lysine Residues in the Translocation of a Cell-Penetrating Peptide from (13)C, (31)P and (19)F Solid-State NMR

Cell-penetrating peptides (CPPs) are small cationic peptides that cross the cell membrane while carrying macromolecular cargoes. We use solid-state NMR to investigate the structure and lipid interaction of two cationic residues, Arg(10) and Lys(13), in the CPP penetratin. (13)C chemical shifts indic...

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Détails bibliographiques
Auteurs principaux: Su, Yongchao, Doherty, Tim, Waring, Alan J., Ruchala, Piotr, Hong, Mei
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723743/
https://ncbi.nlm.nih.gov/pubmed/19364134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900080d
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