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Acetylation of Pregnane X Receptor protein determines selective function independent of ligand activation

Pregnane X Receptor (PXR), like other members of its class of nuclear receptors, undergoes post-translational modification [PTM] (e.g., phosphorylation). However, it is unknown if acetylation (a major and common form of protein PTM) is observed on PXR and, if it is, whether it is of functional conse...

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Библиографические подробности
Главные авторы: Biswas, Arunima, Pasquel, Danielle, Tyagi, Rakesh Kumar, Mani, Sridhar
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062701/
https://ncbi.nlm.nih.gov/pubmed/21329659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.048
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