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Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase

The Saccharomyces cerevisiae SGS1 gene encodes a RecQ-like DNA helicase, human homologues of which are implicated in the genetic instability disorders, Bloom syndrome (BS), Rothmund-Thomson syndrome (RTS), and Werner syndrome (WS). Telomerase-negative yeast cells can recover from senescence via two...

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Detalhes bibliográficos
Main Authors: Cohen, Haim, Sinclair, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30626/
https://ncbi.nlm.nih.gov/pubmed/11248051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061579598
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