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Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
The Saccharomyces cerevisiae SGS1 gene encodes a RecQ-like DNA helicase, human homologues of which are implicated in the genetic instability disorders, Bloom syndrome (BS), Rothmund-Thomson syndrome (RTS), and Werner syndrome (WS). Telomerase-negative yeast cells can recover from senescence via two...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30626/ https://ncbi.nlm.nih.gov/pubmed/11248051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061579598 |
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