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Methylene blue photosensitised strand cleavage of DNA: effects of dye binding and oxygen.
It is shown that methylene blue (MB+) photosensitises DNA in either aerated or deaerated solutions, causing direct cleavage of phosphodiester bonds and rendering additional bonds labile to alkali. Evidence from unwinding and fluorimetric studies indicates that MB+ binds to DNA in at least 2 ways. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1987
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306257/ https://ncbi.nlm.nih.gov/pubmed/2821508 |
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