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Inhibition of Multidrug Resistance by SV40 Pseudovirion Delivery of an Antigene Peptide Nucleic Acid (PNA) in Cultured Cells

Peptide nucleic acid (PNA) is known to bind with extraordinarily high affinity and sequence-specificity to complementary nucleic acid sequences and can be used to suppress gene expression. However, effective delivery into cells is a major obstacle to the development of PNA for gene therapy applicati...

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Detalhes bibliográficos
Main Authors: Macadangdang, Benjamin, Zhang, Ning, Lund, Paul E., Marple, Andrew H., Okabe, Mitsunori, Gottesman, Michael M., Appella, Daniel H., Kimchi-Sarfaty, Chava
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062552/
https://ncbi.nlm.nih.gov/pubmed/21445346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017981
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