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Inhibition of Multidrug Resistance by SV40 Pseudovirion Delivery of an Antigene Peptide Nucleic Acid (PNA) in Cultured Cells

Peptide nucleic acid (PNA) is known to bind with extraordinarily high affinity and sequence-specificity to complementary nucleic acid sequences and can be used to suppress gene expression. However, effective delivery into cells is a major obstacle to the development of PNA for gene therapy applicati...

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Autori principali: Macadangdang, Benjamin, Zhang, Ning, Lund, Paul E., Marple, Andrew H., Okabe, Mitsunori, Gottesman, Michael M., Appella, Daniel H., Kimchi-Sarfaty, Chava
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062552/
https://ncbi.nlm.nih.gov/pubmed/21445346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017981
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