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A mitotic transcriptional switch in polycystic kidney disease
Hepatocyte nuclear factor-1β(HNF-1β) is a transcription factor required for the expression of several renal cystic genes and whose prenatal deletion leads to polycystic kidney disease (PKD)1. We show here that inactivation of Hnf1b from postnatal day 10 onward does not elicit cystic dilations in tub...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062536/ https://ncbi.nlm.nih.gov/pubmed/19966811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2068 |
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