Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

Protocadherin 15 (PCDH15) is expressed in hair cells of the inner ear and in photoreceptors of the retina. Mutations in PCDH15 cause Usher Syndrome (deaf-blindness) and recessive deafness. In developing hair cells, PCDH15 localizes to extracellular linkages that connect the stereocilia and kinociliu...

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Bibliografiska uppgifter
Huvudupphovsmän: Webb, Stuart W., Grillet, Nicolas, Andrade, Leonardo R., Xiong, Wei, Swarthout, Lani, Della Santina, Charley C., Kachar, Bechara, Müller, Ulrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2011
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062428/
https://ncbi.nlm.nih.gov/pubmed/21427143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.060061
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