Dichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway

B and T lymphocyte attenuator (BTLA) is a coinhibitory receptor that interacts with herpesvirus entry mediator (HVEM), and this interaction regulates pathogenesis in various immunologic diseases. In graft-versus-host disease (GVHD), BTLA unexpectedly mediates positive effects on donor T-cell surviva...

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Détails bibliographiques
Auteurs principaux: Sakoda, Yukimi, Park, Jang-June, Zhao, Yuming, Kuramasu, Atsuo, Geng, Degui, Liu, Yingjia, Davila, Eduardo, Tamada, Koji
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062413/
https://ncbi.nlm.nih.gov/pubmed/21220749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-301325
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