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Role of defective autophagia and the intestinal flora in Crohn disease

The precise mechanisms underlying the development of Crohn disease (CD) remain controversial, but sufficient data have been collected to suggest that an uncontrolled immune response within the intestinal mucosa leads to inflammation in a genetically susceptible host. Although lack of mucosal regulat...

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Detalhes bibliográficos
Main Authors: Regeling, Anouk, Somasundaram, Rajesh, de Haar, Colin, van der Woude, C Janneke, Braat, Henri, Peppelenbosch, Maikel P
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062387/
https://ncbi.nlm.nih.gov/pubmed/21487507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.4.13990
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