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Differential requirements for CD45 in NK-cell function reveal distinct roles for Syk-family kinases
The protein tyrosine phosphatase CD45 is an important regulator of Src-family kinase activity. We found that in the absence of CD45, natural killer (NK) cells are defective in protecting the host from mouse cytomegalovirus infection. We show that although CD45 is necessary for all immunoreceptor tyr...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062311/ https://ncbi.nlm.nih.gov/pubmed/21245479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-292219 |
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