IκBζ augments IL-12– and IL-18–mediated IFN-γ production in human NK cells

Interferon-γ (IFN-γ) production by natural killer (NK) cells and cytotoxic lymphocytes is a key component of innate and adaptive immune responses. Because inhibitor of κB-ζ (IκBζ), a Toll-like receptor (TLR)/interleukin-1 receptor (IL-1R) inducible transcription factor, regulates IFN-γ production in...

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Bibliographic Details
Main Authors: Kannan, Yashaswini, Yu, Jianhua, Raices, Raquel M., Seshadri, Sudarshan, Wei, Min, Caligiuri, Michael A., Wewers, Mark D.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2011
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062297/
https://ncbi.nlm.nih.gov/pubmed/21224476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-294702
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