Structure-Function Study of Mammalian Munc18-1 and C. elegans UNC-18 Implicates Domain 3b in the Regulation of Exocytosis

Munc18-1 is an essential synaptic protein functioning during multiple stages of the exocytotic process including vesicle recruitment, docking and fusion. These functions require a number of distinct syntaxin-dependent interactions; however, Munc18-1 also regulates vesicle fusion via syntaxin-indepen...

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Detalhes bibliográficos
Main Authors: Graham, Margaret E., Prescott, Gerald R., Johnson, James R., Jones, Mathew, Walmesley, Alice, Haynes, Lee P., Morgan, Alan, Burgoyne, Robert D., Barclay, Jeff W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061876/
https://ncbi.nlm.nih.gov/pubmed/21445306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017999
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