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A Toll-Like Receptor-4-Interacting Surfactant Protein-A-Derived Peptide Suppresses Tumor Necrosis Factor-α Release from Mouse JAWS II Dendritic Cells

Surfactant protein-A (SP-A) and Toll-like receptor-4 (TLR4) proteins are recognized as pathogen-recognition receptors. An exaggerated activation of TLR4 induces inflammatory response, whereas SP-A protein down-regulates inflammation. We hypothesized that SP-A–TLR4 interaction may lead to inhibition...

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Detalhes bibliográficos
Main Authors: Awasthi, Shanjana, Brown, Kevin, King, Catherine, Awasthi, Vibhudutta, Bondugula, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061537/
https://ncbi.nlm.nih.gov/pubmed/21159752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173765
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