Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular Degeneration

PURPOSE. Increasing evidence suggests a central role for mitochondrial (mt) dysfunction in age-related macular degeneration (AMD). Previous proteomic data from the retinal pigment epithelium (RPE) revealed significant changes to mt proteins, suggesting potential functional defects and damage to mito...

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Bibliographic Details
Main Authors: Karunadharma, Pabalu P., Nordgaard, Curtis L., Olsen, Timothy W., Ferrington, Deborah A.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061495/
https://ncbi.nlm.nih.gov/pubmed/20505194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5429
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