Quality control and quality assurance in genotypic data for genome-wide association studies

Genome-wide scans of nucleotide variation in human subjects are providing an increasing number of replicated associations with complex disease traits. Most of the variants detected have small effects and, collectively, they account for a small fraction of the total genetic variance. Very large sampl...

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Detalhes bibliográficos
Main Authors: Laurie, Cathy C., Doheny, Kimberly F., Mirel, Daniel B., Pugh, Elizabeth W., Bierut, Laura J., Bhangale, Tushar, Boehm, Frederick, Caporaso, Neil E., Cornelis, Marilyn C., Edenberg, Howard J., Gabriel, Stacy B., Harris, Emily L., Hu, Frank B., Jacobs, Kevin, Kraft, Peter, Landi, Maria Teresa, Lumley, Thomas, Manolio, Teri A., McHugh, Caitlin, Painter, Ian, Paschall, Justin, Rice, John P., Rice, Kenneth M., Zheng, Xiuwen, Weir, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061487/
https://ncbi.nlm.nih.gov/pubmed/20718045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20516
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