Quality control and quality assurance in genotypic data for genome-wide association studies

Genome-wide scans of nucleotide variation in human subjects are providing an increasing number of replicated associations with complex disease traits. Most of the variants detected have small effects and, collectively, they account for a small fraction of the total genetic variance. Very large sampl...

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Hlavní autoři: Laurie, Cathy C., Doheny, Kimberly F., Mirel, Daniel B., Pugh, Elizabeth W., Bierut, Laura J., Bhangale, Tushar, Boehm, Frederick, Caporaso, Neil E., Cornelis, Marilyn C., Edenberg, Howard J., Gabriel, Stacy B., Harris, Emily L., Hu, Frank B., Jacobs, Kevin, Kraft, Peter, Landi, Maria Teresa, Lumley, Thomas, Manolio, Teri A., McHugh, Caitlin, Painter, Ian, Paschall, Justin, Rice, John P., Rice, Kenneth M., Zheng, Xiuwen, Weir, Bruce S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061487/
https://ncbi.nlm.nih.gov/pubmed/20718045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20516
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