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Lack of glutathione peroxidase-1 accelerates cardiac-specific hypertrophy and dysfunction in angiotensin II hypertension
Glutathione peroxidase-1 (Gpx1) plays an important role in cellular defense by converting hydrogen peroxide (H(2)O(2)) and organic hydroperoxides to non-reactive products and Gpx1(−/−) mice, which are characterized by reduced tissue glutathione peroxidase activity, are known to exhibit enhanced oxid...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061336/ https://ncbi.nlm.nih.gov/pubmed/19917877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.135715 |
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