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Endothelin-1 Induces Contraction of Female Rat Internal Pudendal and Clitoral Arteries through ET(A) Receptor and Rho-Kinase Activation

INTRODUCTION: Endothelin-1 (ET-1), a potent vasoconstrictor peptide, acts mainly through the Gprotein-coupled ET(A) receptor (ET(A)R). Increased vascular ET-1 production and constrictor sensitivity have been observed in various cardiovascular diseases, including hypertension, as well as erectile dys...

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Main Authors: Allahdadi, Kyan J., Hannan, Johanna L., Tostes, Rita C., Webb, R. Clinton
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061306/
https://ncbi.nlm.nih.gov/pubmed/20412427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1743-6109.2010.01816.x
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