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A simple method using Pyrosequencing(TM) to identify de novo SNPs in pooled DNA samples
A practical way to reduce the cost of surveying single-nucleotide polymorphism (SNP) in a large number of individuals is to measure the allele frequencies in pooled DNA samples. Pyrosequencing(TM) has been frequently used for this application because signals generated by this approach are proportion...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061071/ https://ncbi.nlm.nih.gov/pubmed/21131285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1249 |
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