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A simple method using Pyrosequencing(TM) to identify de novo SNPs in pooled DNA samples

A practical way to reduce the cost of surveying single-nucleotide polymorphism (SNP) in a large number of individuals is to measure the allele frequencies in pooled DNA samples. Pyrosequencing(TM) has been frequently used for this application because signals generated by this approach are proportion...

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Detalhes bibliográficos
Main Authors: Lin, Yeong-Shin, Liu, Fu-Guo Robert, Wang, Tzi-Yuan, Pan, Cheng-Tsung, Chang, Wei-Ting, Li, Wen-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061071/
https://ncbi.nlm.nih.gov/pubmed/21131285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1249
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