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The high fidelity and unique error signature of human DNA polymerase ε

Bulk replicative DNA synthesis in eukaryotes is highly accurate and efficient, primarily because of two DNA polymerases (Pols): Pols δ and ε. The high fidelity of these enzymes is due to their intrinsic base selectivity and proofreading exonuclease activity which, when coupled with post-replication...

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Detalhes bibliográficos
Main Authors: Korona, Dagmara A., LeCompte, Kimberly G., Pursell, Zachary F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061053/
https://ncbi.nlm.nih.gov/pubmed/21036870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1034
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