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TRAPping telomerase within the intestinal stem cell niche

Recent work from Hans Clevers' lab reveals high telomerase activity and telomere length in dividing LGR5-positive intestinal stem cells. They further report random chromosome segregation and thus challenge the ‘immortal strand' hypothesis at least for this stem cell population.

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Bibliographische Detailangaben
Hauptverfasser: Pech, Matthew F, Artandi, Steven E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061044/
https://ncbi.nlm.nih.gov/pubmed/21407250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.51
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