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Treatment with Connexin 46 siRNA Suppresses the Growth of Human Y79 Retinoblastoma Cell Xenografts in vivo

Tumors with a hypoxic component, including human Y79 retinoblastoma cells, express a specific gap junction protein, Connexin 46 (Cx46), which is usually only found in naturally hypoxic tissues such as the differentiated lens. The aim of this study was to investigate if Cx46 down-regulation would sup...

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Detalhes bibliográficos
Main Authors: Burr, Diana B., Molina, Samuel A., Banerjee, Debarshi, Low, Derek M., Takemoto, Dolores J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060947/
https://ncbi.nlm.nih.gov/pubmed/21320488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.02.003
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