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FcγRIIB Regulation of BCR/TLR-Dependent Autoreactive B Cell Responses
Crosslinking of FcγRIIB and the BCR by immune complexes (ICs) can downregulate antigen-specific B cell responses. Accordingly, FcγRIIB deficiencies have been associated with B cell hyperactivity in patients with SLE and mouse models of lupus. However, we have previously shown that murine IgG2a-autor...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060940/ https://ncbi.nlm.nih.gov/pubmed/20809520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940184 |
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