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Identification of Local Conformational Similarity in Structurally Variable Regions of Homologous Proteins Using Protein Blocks

Structure comparison tools can be used to align related protein structures to identify structurally conserved and variable regions and to infer functional and evolutionary relationships. While the conserved regions often superimpose well, the variable regions appear non superimposable. Differences i...

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Autori principali: Agarwal, Garima, Mahajan, Swapnil, Srinivasan, Narayanaswamy, de Brevern, Alexandre G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060819/
https://ncbi.nlm.nih.gov/pubmed/21445259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017826
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