Identification of Local Conformational Similarity in Structurally Variable Regions of Homologous Proteins Using Protein Blocks

Structure comparison tools can be used to align related protein structures to identify structurally conserved and variable regions and to infer functional and evolutionary relationships. While the conserved regions often superimpose well, the variable regions appear non superimposable. Differences i...

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Bibliographic Details
Main Authors: Agarwal, Garima, Mahajan, Swapnil, Srinivasan, Narayanaswamy, de Brevern, Alexandre G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060819/
https://ncbi.nlm.nih.gov/pubmed/21445259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017826
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