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The Adapter Protein APPL1 Links FSH Receptor to Inositol 1,4,5-Trisphosphate Production and Is Implicated in Intracellular Ca(2+) Mobilization

FSH binds to its receptor (FSHR) on target cells in the ovary and testis, to regulate oogenesis and spermatogenesis, respectively. The signaling cascades activated after ligand binding are extremely complex and have been shown to include protein kinase A, mitogen-activated protein kinase, phosphatid...

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Sonraí Bibleagrafaíochta
Main Authors: Thomas, Richard M., Nechamen, Cheryl A., Mazurkiewicz, Joseph E., Ulloa-Aguirre, Alfredo, Dias, James A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Endocrine Society 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060640/
https://ncbi.nlm.nih.gov/pubmed/21285318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1353
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