The Adapter Protein APPL1 Links FSH Receptor to Inositol 1,4,5-Trisphosphate Production and Is Implicated in Intracellular Ca(2+) Mobilization

FSH binds to its receptor (FSHR) on target cells in the ovary and testis, to regulate oogenesis and spermatogenesis, respectively. The signaling cascades activated after ligand binding are extremely complex and have been shown to include protein kinase A, mitogen-activated protein kinase, phosphatid...

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Hlavní autoři: Thomas, Richard M., Nechamen, Cheryl A., Mazurkiewicz, Joseph E., Ulloa-Aguirre, Alfredo, Dias, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Reproduction-Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060640/
https://ncbi.nlm.nih.gov/pubmed/21285318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1353
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