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β2-Adrenergic Receptor Signaling in Osteoblasts Contributes to the Catabolic Effect of Glucocorticoids on Bone

The sympathetic nervous system is a physiological regulator of bone homeostasis. Autonomic nerves are indeed present in bone, bone cells express the β2-adrenergic receptors (β2AR), and pharmacological or genetic disruption of sympathetic outflow to bone induces bone gain in rodents. These recent fin...

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Detalhes bibliográficos
Main Authors: Ma, Yun, Nyman, Jeffry S., Tao, Huan, Moss, Heather H., Yang, Xiangli, Elefteriou, Florent
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060633/
https://ncbi.nlm.nih.gov/pubmed/21266510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0881
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