Small Interfering RNAs (siRNAs) Targeting TGF-β(1) mRNA Suppress Asbestos-Induced Expression of TGF-β(1) and CTGF in Fibroblasts

Interstitial lung disease (ILD) afflicts millions of people worldwide. ILD can be caused by a number of agents, including inhaled asbestos, and may ultimately result in respiratory failure and death. Currently, there are no effective treatments for ILD. Transforming growth factor-β(1) (TGF-β(1)) is...

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Hlavní autoři: Lai, Tai-Cheng, Pociask, Derek A., Ferris, MaryBeth, Nguyen, Hong T., Miller, Charles A., Brody, Arnold R., Sullivan, Deborah E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060608/
https://ncbi.nlm.nih.gov/pubmed/19817698
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