The Aspergillus fumigatus Sialidase Is a 3-Deoxy-d-glycero-d-galacto-2-nonulosonic Acid Hydrolase (KDNase): STRUCTURAL AND MECHANISTIC INSIGHTS

Aspergillus fumigatus is a filamentous fungus that can cause severe respiratory disease in immunocompromised individuals. A putative sialidase from A. fumigatus was recently cloned and shown to be relatively poor in cleaving N-acetylneuraminic acid (Neu5Ac) in comparison with bacterial sialidases. H...

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Detalhes bibliográficos
Main Authors: Telford, Judith C., Yeung, Juliana H. F., Xu, Guogang, Kiefel, Milton J., Watts, Andrew G., Hader, Stefan, Chan, Jefferson, Bennet, Andrew J., Moore, Margo M., Taylor, Garry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060529/
https://ncbi.nlm.nih.gov/pubmed/21247893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207043
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