Single Particle Tracking Confirms That Multivalent Tat Protein Transduction Domain-induced Heparan Sulfate Proteoglycan Cross-linkage Activates Rac1 for Internalization

The mechanism by which HIV-1-Tat protein transduction domain (TatP) enters the cell remains unclear because of an insufficient understanding of the initial kinetics of peptide entry. Here, we report the successful visualization and tracking of TatP molecular kinetics on the cell surface with 7-nm sp...

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Bibliografische gegevens
Hoofdauteurs: Imamura, Junji, Suzuki, Yasuhiro, Gonda, Kohsuke, Roy, Chandra Nath, Gatanaga, Hiroyuki, Ohuchi, Noriaki, Higuchi, Hideo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Molecular Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060510/
https://ncbi.nlm.nih.gov/pubmed/21199870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187450
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