Identification of the Synthetic Cannabinoid R(+)WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-β Expression: RELEVANCE TO THERAPEUTIC EFFECTS IN MODELS OF MULTIPLE SCLEROSIS

β-Interferons (IFN-βs) represent one of the first line treatments for relapsing-remitting multiple sclerosis, slowing disease progression while reducing the frequency of relapses. Despite this, more effective, well tolerated therapeutic strategies are needed. Cannabinoids palliate experimental autoi...

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Detalhes bibliográficos
Main Authors: Downer, Eric J., Clifford, Eileen, Gran, Bruno, Nel, Hendrik J., Fallon, Padraic G., Moynagh, Paul N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060486/
https://ncbi.nlm.nih.gov/pubmed/21245146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188599
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