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The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway

Autophagy is an innate immune defense against bacterial invasion. Recent studies show that two adaptor proteins, p62 and NDP52, are required for autophagy of the bacterial pathogen Salmonella enterica serovar Typhimurium (S. typhimurium). However, it is not known why two different adaptors are requi...

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Hlavní autoři: Cemma, Marija, Kim, Peter Kijun, Brumell, John Hunter
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060414/
https://ncbi.nlm.nih.gov/pubmed/21079414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.3.14046
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