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The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway

Autophagy is an innate immune defense against bacterial invasion. Recent studies show that two adaptor proteins, p62 and NDP52, are required for autophagy of the bacterial pathogen Salmonella enterica serovar Typhimurium (S. typhimurium). However, it is not known why two different adaptors are requi...

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Detalhes bibliográficos
Main Authors: Cemma, Marija, Kim, Peter Kijun, Brumell, John Hunter
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060414/
https://ncbi.nlm.nih.gov/pubmed/21079414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.3.14046
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