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NDP52: the missing link between ubiquitinated bacteria and autophagy

Mammalian cells ubiquitinate bacteria that erroneously enter the cytosol, and target these intruding microbes for destruction by autophagy. New work shows that the protein NDP52 directly binds to ubiquitinated bacteria and facilitates the assembly of an autophagic membrane that surrounds these invad...

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Autors principals: Ivanov, Stanimir, Roy, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803095/
https://ncbi.nlm.nih.gov/pubmed/19841643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1109-1137
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