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A unique spectrum of somatic PIK3CA (p110α) mutations within primary endometrial carcinomas

PURPOSE: The goal of this study was to comprehensively define the incidence of mutations in all exons of PIK3CA in both endometrioid endometrial cancer (EEC) and non-endometrioid endometrial cancer (NEEC). EXPERIMENTAL DESIGN: We resequenced all coding exons of PIK3CA and PTEN, and exons 1 and 2 of...

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Detalhes bibliográficos
Main Authors: Rudd, Meghan L., Price, Jessica C., Fogoros, Sarah, Godwin, Andrew K., Sgroi, Dennis C., Merino, Maria J., Bell, Daphne W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060282/
https://ncbi.nlm.nih.gov/pubmed/21266528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0540
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