Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1

BACKGROUND: Endometrial cancer (EC) is the 8(th) leading cause of cancer death amongst American women. Most ECs are endometrioid, serous, or clear cell carcinomas, or an admixture of histologies. Serous and clear ECs are clinically aggressive tumors for which alternative therapeutic approaches are n...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Rudd, Meghan L, Mohamed, Hassan, Price, Jessica C, O’Hara, Andrea J, Le Gallo, Matthieu, Urick, Mary Ellen, Cruz, Pedro, Zhang, Suiyuan, Hansen, Nancy F, Godwin, Andrew K, Sgroi, Dennis C, Wolfsberg, Tyra G, Mullikin, James C, Merino, Maria J, Bell, Daphne W
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258955/
https://ncbi.nlm.nih.gov/pubmed/25427824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-884
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