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The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish
Mutations in the serine-threonine kinase (LKB1) lead to a gastrointestinal hamartomatous polyposis disorder with increased predisposition to cancer (Peutz–Jeghers syndrome). LKB1 has many targets, including the AMP-activated protein kinase (AMPK) that is phosphorylated under low-energy conditions. A...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060253/ https://ncbi.nlm.nih.gov/pubmed/21368212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010210108 |
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