Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive tumors of childhood that are almost universally fatal. Our understanding of this devastating cancer is limited by a dearth of available tissue for study and by the lack of a faithful animal model. Intriguingly, DIPGs are restricted to t...

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Bibliografiska uppgifter
Huvudupphovsmän: Monje, Michelle, Mitra, Siddhartha S., Freret, Morgan E., Raveh, Tal B., Kim, James, Masek, Marilyn, Attema, Joanne L., Li, Gordon, Haddix, Terri, Edwards, Michael S. B., Fisher, Paul G., Weissman, Irving L., Rowitch, David H., Vogel, Hannes, Wong, Albert J., Beachy, Philip A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060250/
https://ncbi.nlm.nih.gov/pubmed/21368213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101657108
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