Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive tumors of childhood that are almost universally fatal. Our understanding of this devastating cancer is limited by a dearth of available tissue for study and by the lack of a faithful animal model. Intriguingly, DIPGs are restricted to t...

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Hauptverfasser: Monje, Michelle, Mitra, Siddhartha S., Freret, Morgan E., Raveh, Tal B., Kim, James, Masek, Marilyn, Attema, Joanne L., Li, Gordon, Haddix, Terri, Edwards, Michael S. B., Fisher, Paul G., Weissman, Irving L., Rowitch, David H., Vogel, Hannes, Wong, Albert J., Beachy, Philip A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060250/
https://ncbi.nlm.nih.gov/pubmed/21368213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101657108
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