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Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization

BACKGROUND: Trypanosoma cruzi is a protozoan parasite and the etiologic agent of Chagas disease, an important public health problem in Latin America. T. cruzi is diploid, almost exclusively asexual, and displays an extraordinarily diverse population structure both genetically and phenotypically. Yet...

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Autors principals: Minning, Todd A, Weatherly, D Brent, Flibotte, Stephane, Tarleton, Rick L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060142/
https://ncbi.nlm.nih.gov/pubmed/21385342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-139
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