RDX Binds to the GABA(A) Receptor–Convulsant Site and Blocks GABA(A) Receptor–Mediated Currents in the Amygdala: A Mechanism for RDX-Induced Seizures

BACKGROUND: Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a high-energy, trinitrated cyclic compound that has been used worldwide since World War II as an explosive in both military and civilian applications. RDX can be released in the environment by way of waste streams generated during the manu...

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Main Authors: Williams, Larry R., Aroniadou-Anderjaska, Vassiliki, Qashu, Felicia, Finne, Huckelberry, Pidoplichko, Volodymyr, Bannon, Desmond I., Braga, Maria F. M.
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059999/
https://ncbi.nlm.nih.gov/pubmed/21362589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002588
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