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RDX Binds to the GABA(A) Receptor–Convulsant Site and Blocks GABA(A) Receptor–Mediated Currents in the Amygdala: A Mechanism for RDX-Induced Seizures

BACKGROUND: Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a high-energy, trinitrated cyclic compound that has been used worldwide since World War II as an explosive in both military and civilian applications. RDX can be released in the environment by way of waste streams generated during the manu...

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Détails bibliographiques
Auteurs principaux: Williams, Larry R., Aroniadou-Anderjaska, Vassiliki, Qashu, Felicia, Finne, Huckelberry, Pidoplichko, Volodymyr, Bannon, Desmond I., Braga, Maria F. M.
Format: Artigo
Langue:Inglês
Publié: National Institute of Environmental Health Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059999/
https://ncbi.nlm.nih.gov/pubmed/21362589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002588
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