Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case–control study

BACKGROUND: Folate-associated one-carbon metabolism (FOCM) is an important pathway in colorectal neoplasia risk but data on genetic variation in this pathway are largely limited to studies of single SNPs in selected genes. METHODS: We used a comprehensive tagSNP approach to study the association bet...

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Autors principals: Levine, A. Joan, Lee, Won, Figueiredo, Jane C., Conti, David V., Vandenberg, David J., Davis, Brian D., Edlund, Christopher K., Henning, Susanne M., Heber, David, Stern, Mariana C., Haile, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2011
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059778/
https://ncbi.nlm.nih.gov/pubmed/21274745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-011-9726-7
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